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Our Research & Publications

We have published over 250 scientific articles in peer-reviewed journals and regularly present our research at scientific meetings.

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Cardiovascular risk factor insights into the tesco 1.0 dataset

Cardiac

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Considering the risk of QTc prolongation in patients with diabetes mellitus

Cardiac

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Effect of hyperglycaemia in combination with moxifloxacin on cardiac repolarization in male and female patients with type I diabetes

Cardiac

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Kinetics of anti-SARS-CoV-2 IgG antibody levels and potential influential factors in subjects with COVID-19: A 11-month follow-up study

Covid-19

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Race and diurnal variability of biomarkers for diabetes and cardiovascular disease

Cardiac

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Confirmation of the cardiac safety of nolasiban in a randomised cohort of healthy female volunteers

Cardiac

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Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter

Cardiac

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A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity

Cardiac

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Effects of progesterone and estradiol on QT subintervals over the course of a menstrual cycle

Cardiac

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Do hERG blocking agents further increase the risk of sudden cardiac death in patients with type 1 diabetes?

Cardiac

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Practical risk management in early phase clinical trials

Trial Methodologies

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A Box-Cox Approach to QT Interval Correction for Heart Rate

Trial Methodologies

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Three steps to writing adaptive study protocols in the early phase clinical development of new medicines

Trial Methodologies

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The practical application of adaptive study design in early phase clinical trials: a retrospective analysis of time savings

Trial Methodologies

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Mason-Likar electrode configuration can confound the recognition of electrode cable interchange

Trial Methodologies

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Comparison Of Ecg Parameters Using Ge Getemed Continuous Ecg Holter And Mac-1200 Bedside Ecg

Trial Methodologies

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The influence of a low fat diet and hospitalisation on liver function tests in healthy Japanese and Caucasian male volunteers (2013)

Liver

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Investigating the Effect of Intravenous APD421 (Amisulpride) and the Ethnic Differences Between Japanese and Caucasians on Cardiac Conduction

Ethnicity

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Cardiac Safety of Rupatadine in a Single-Ascending-Dose and Multiple-Ascending-Dose Study in Healthy Japanese Subjects

Ethnicity

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Diurnal and Racial Variance of White Blood Cell Parameters in Early Phase Clinical Trials

Ethnicity

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Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects (2011)

Cardiac

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Insulin at normal physiological levels does not prolong QTc interval in thorough QT studies performed in healthy volunteers (2012)

Cardiac

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Shortening of the QT Interval After Food Can Be Used to Demonstrate Assay Sensitivity in Thorough QT Studies (2012)

Cardiac

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Thorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjects (2013)

Cardiac

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Estimation of the Power of the Food Effect on QTc to Show Assay Sensitivity (2017)

Cardiac

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Diurnal Profile of the QTc Interval Following Moxifloxacin Administration (2019)

Cardiac

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Effects of the Fluoroquinolones Moxifloxacin and Levofloxacin on the QT Subintervals: Sex Differences in Ventricular Repolarization (2019)

Cardiac

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The Cardiovascular Effects of a Meal: J-Tpeak and Tpeak-Tend Assessment and Further Insights Into the Physiological Effects (2019)

Cardiac

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